363569
IFNa2 (Interferon Alpha 2, IFNA2A, IFNA2B, IFNA2C, LeIF A, Alpha-2a Interferon, Interferon Alpha 2b, Interferon Alpha A)
Size
£479.00
- SKU:
- 363569
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Cys24-Glu188 of human IFNa2, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- The successful use of intranasal alpha-2-interferon produced by recombinant DNA technology in the prophylaxis of the common cold was reported by Douglas et al. (1986) and Hayden et al. (1986). Ezekowitz et al. (1992) demonstrated the usefulness of recombinant alpha-interferon (interferon alfa-2a) for inducing regression of life-threatening corticosteroid-resistant hemangiomas in infancy. The hemangiomas treated were those that impair the function of vital structures or cause life-endangering complications such as thrombocytopenic coagulopathy with giant hemangioma. The authors concluded that adjuvant recombinant IFN alfa-2b treatment given before or at the time of enucleation might be a treatment option for patients with uveal melanoma with high-risk factors for developing metastatic disease. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:50-400 Immunocytochemistry: 1:50-500 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 ELISA: 1:100-1:5000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice