363492
HPR (Haptoglobin Related Protein, HP)
Size
£524.00
- SKU:
- 363492
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Asn70-Val332 of human HPR, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- McEvoy and Maeda (1988) analyzed the evolutionary history of the haptoglobin gene family by characterizing the haptoglobin genes in primates. Whereas the HPR gene in the human is 2.2 kb downstream of the HP gene, chimpanzees, gorillas, orangutans, and Old World monkeys have a third gene, which McEvoy and Maeda (1988) named HPP for haptoglobin primate, located 16 kb downstream of HPR. New World monkeys have only 1 haptoglobin gene. McEvoy and Maeda (1988) interpreted these observations as suggesting triplication of the haptoglobin locus after divergence of the New World monkeys, followed by deletion of 1 locus in humans. They stated that, although in vivo transfection experiments indicated that the HPR promoter is active and cell-specific, no hemoglobin-binding protein of the expected structure had been detected. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice