363481
HMMR (Hyaluronan Mediated Motility Receptor, CD168, RHAMM, IHABP, RHAMM, Intracellular hyaluronic acid-binding protein)
Size
£626.00
- SKU:
- 363481
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Asn577-Lys724 of human HMMR, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- RHAMM) was originally discovered as a soluble protein that altered migratory cell behavior and bound to hyaluronan,RHAMM is less well studied than the main hyaluronan (HA) receptor, CD44. In contrast to CD44 and other cell-surface receptors which contain the classical membrane spanning domain and signal sequence for secretion from the endoplasmic reticulum / Golgi complex, RHAMM does not contain a membrane spanning domain nor does the mRNA transcript contain a signal sequence. RHAMM normally is localized inside the cell and is only release by certain, poorly defined stimuli. The transport of RHAMM to the extracellular space still is unclear but may involve transport channels or proteins, flippase activity, or exocytosis. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice