GMCSF (Colony Stimulating Factor 2, Granulocyte Macrophage, CSF2, GM-CSF, Sargramostim, Molgramostin, Granulocyte-Macrophage Colony Stimulating Factor)

Size

£581.00

SKU:: 363322
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Pro19-Lys141 of mouse GMCSF, expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:: Granulocyte-macrophage colony stimulating factor (GM-CSF) was initially identified by its ability to stimulate the formation of granulocyte and macrophage colonies from hematopoietic progenitor cells in semi-solid media. In vivo and in vitro studies have now demonstrated that GM-CSF is a pleiotropic cytokine that induces myeloid precursor cells to proliferate and differentiate into neutrophils, monocyte/macrophages and eosinophils. GM-CSF has also been shown to stimulate the proliferation and differentiation of erythroid and megakaryocyte progenitor cells. In addition, GM-CSF is a survival factor for and activates the effector functions of mature neutrophils, monocytes/macrophages and eosinophils. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice