GGPS1 (Geranylgeranyl Diphosphate Synthase 1, GGPPS1, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase)

Size

£537.00

SKU:: 363279
Purity:: Purified by Protein A and peptide affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to aa78-258 of mouse GGPS1, expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:: Geranylgeranyl pyrophosphate synthetase is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The deduced protein shows 16% identity with farnesyl diphosphate synthase and contains 3 N-glycosylation sites as well as the 5 domains common to trans-prenyltransferases. expression in heart, skeletal muscle, and testis and the shorter transcript as the major species in these tissues. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice