363126
FLII (Flightess I Homolog, FLI, FLIL, Fli1)
Size
£626.00
- SKU:
- 363126
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Leu896-Phe1176 of human FLII, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- FLII encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17. The amino acid sequence deduced from the FLI cDNA has 52% similarity to that of the human gelsolin protein and also has an N-terminal leucine-rich domain with 16 consecutive leucine-rich repeats. FLII gene encodes a predicted 1269aa protein. Northern blot analysis revealed FLII expression as an approximately 4.4-kb mRNA in all tissues tested, with strongest expression in skeletal muscle. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice