363113
FGg (Fibrinogen Gamma, FG-G)
Size
£505.00
- SKU:
- 363113
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Lys168-Asp444 of bovine FGg, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Fibrinogen gamma chain is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- KIH DVTGRDCQDV ANKGAKESGL YFIRPLKAKQ FLVYCEIDGS GNGWTVFQKR LDGSLDFKKN WIQYKEGFGH LSPTGTGNTE FWLGNEKIHL ISTQSSIPYV LRIQLEDWNG RTSTADYASF KVTGENDKYR LTYAYFIGGD AGDAFDGYDF GDDSSDKFFT SHNGMQFSTW DSDNDKYDGN CAEQVGIGWW MNKCHAGHLN GVYYQGGTYS KTSTPNGYDN GIIWATWKSR WYSMKKTTMK IIPLNRLAIG EGQQHQLGGA KQVGVEHHVE IEYD Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice