DPYSL3 (Dihydropyrimidinase Like Protein 3, CRMP4, DRP3, ULIP, Dihydropyrimidinase-related protein 3, Collapsin response mediator protein 4, Unc-33-like phosphoprotein 1)

Size

£495.00

SKU:: 362886
Application:: WB
Purity:: Purified by Protein A and peptide affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Met1-Thr218 of mouse DPYSL3, expressed in E. coli.
Format:: Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
Extra Details:: Byk et al. (1996) isolated and characterized a novel mouse phosphoprotein with significant homology to Unc33, a protein important for neuritic outgrowth and guidance in C. elegans. The cDNA isolated from mouse brain has an open reading frame that encodes a protein of 570aa with a predicted molecular mass of 61.94kD and a theoretical pI of 6.3. This sequence shows consensus sites for several protein kinases, corroborating biochemical studies indicating the phosphorylation of partially purified ULIP with protein kinase A (PKA), casein kinase-2, and CDC2 kinase. ULIP was found to be cytoplasmic in PC12 cells, and it exclusively associated with neurons, particularly at neuromuscular junctions. Byk et al. (1996) stated that 3 human ESTs show between 76 and 96% overall identity to the mouse ULIP sequence. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- MSYQGKKNIP RITSDRLLIK GGRIVNDDQS FYADIYMEDG LIKQIGDNLI VPGGVKTIEA NGKMVIPGGI DVHTHFQMPY KGMTTVDDFF QGTKAALAGG TTMIIDHVVP EPESSLTEAY EKWREWADGK SCCDYALHVD ITHWNDSVKQ EVQSLSKEKG VNSFMVYMAY KDLYQVSNTE LYEIFTCLGE LGAIAQVHAE NGDIIAQEQA RMLEMGIT Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice