362776
CYP11A1 (Cytochrome P450 11A1, CYP11A, P450SCC, Cholesterol desmolase, Cholesterol Side Chain Cleavage Enzyme, Cytochrome P450 Family 11 Subfamily A Polypeptide 1)
Size
£626.00
- SKU:
- 362776
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Val392-Gln521 of human CYP11A1, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Cytochrome P450, family 11, subfamily A, polypeptide 1 (P45011a1), often referred to as P450scc is a mitochondrial enzyme associated with the conversion of cholesterol to pregnenolone. The gene name is CYP11A1. The term "desmolase" is becoming outdated and the enzyme is now commonly referred to as P450scc, where "scc" refers to side chain cleavage. The protein is a member of the cytochrome family of enzymes. The protein resides on the inner mitochondrial membrane, facing the interior (matrix). The presence of this enzyme defines if a cell is steroidogenic. Consequently, P450scc is found in all steroid-producing cell types such as theca cells and luteal cells in the ovary, Leydig cells in the testis and cell types in the adrenal cortex. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice