362600
CLOCK (Circadian Locomoter Output Cycles Protein Kaput, KAT13D, bHLHe8, Class E basic helix-loop-helix protein 8)
Size
£517.00
- SKU:
- 362600
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ala34-Ala379 of human CLOCK, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- Circadian rhythmicity of biologic processes is a fundamental property of all eukaryotic and some prokaryotic organisms. These rhythms are driven by an internal time-keeping system. Changes in the external environment, particularly in the light-dark cycle, entrain this biologic clock.Under constant environmental conditions devoid of time cues, rhythms driven by the biologic clock show a period near, but usually not equal to, 24 hours. The CLOCK gene encodes a basic helix-loop-helix (bHLH)-PAS transcription factor that is essential for circadian rhythm. The gene encodes an 855aa polypeptide that is a novel member of the bHLH-PAS family of transcription factors and has features predicting DNA binding, protein dimerization, and activation domains. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice