CIB1 (Calcium And Integrin Binding Protein 1, CIB, KIP, SIP2-28, CIBP, PRKDCIP, Calmyrin, DNA-PKcs-interacting protein, Kinase-interacting protein, SNK-interacting protein 2-28)

Size

£626.00

SKU:: 362573
Purity:: Purified by Protein A and peptide affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Gly2-Leu191 of human CIB1, expressed in E. coli.
Format:: Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
Extra Details:: Calcium and integrin-binding protein 1 is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alpha(IIb)beta(3), which may implicate this protein as a regulatory molecule for alpha(IIb)beta(3).Gel filtration and sedimentation equilibrium analyses showed that only a small percentage of CIB1 formed dimers, with most CIB1 remaining monomeric in the presence or absence of Ca(2+). The calculated molecular mass of CIB1 is 21.7kD, but the protein had an apparent molecular mass of either 26.9 or 30.6kD, depending on the method used, most likely due to its irregular shape. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice