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362529

CEPI (Centromere Protein I, FSHPRH1, LRPR1, Mis6, ICEN19, Follicle-stimulating hormone primary response protein, Interphase centromere complex protein 19, Leucine-rich primary response protein 1)

Size

£479.00

SKU:
362529
Purity:
Purified by Protein A and peptide affinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to Leu292-Gly528, of human CENPI, expressed in E. coli.
Format:
Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
Extra Details:
Centromere protein I is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis. By database searching with a sequence identified near the DRP2 gene on chromosome Xq22, Roberts et al. (1996) found that the sequence showed similarity to the rat LRPR1 gene. The deduced 756aa human protein shares 72% sequence identity with the rat protein.Roberts et al. (1996) identified the LRPR1 gene on chromosome Xq22. They found by hybridization to YACs and to cosmids isolated from that region that LRPR1 is transcribed in a proximal-to-distal direction and lies approximately 40 kb proximal to DRP2, while BTK, the gene that is mutant in X-linked agammaglobulinemia, lies approximately 300 kb distal. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- LGPANVRPL KRKWNSLSVI PVLNSSSYTK ECGKKEMSLS DCLNRSGSFP LEQLQSFPQL LQNIHCLELP SQMGSVLNNS LLLHYINCVR DEPVLLRFYY WLSQTLQEEC IWYKVNNYEH GKEFTNFLDT IIRAECFLQE GFYSCEAFLY KSLPLWDGLC CRSQFLQLVS WIPFSSFSEV KPLLFDHLAQ LFFTSTIYFK CSVLQSLKEL LQNWLLWLSM DIHMKPVTNS PLETTLGG Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice