362516
CECR1 (Cat Eye Syndrome Chromosome Region, Candidate 1, IDGFL, ADGF, ADA2, Cat Eye Syndrome Critical Region Protein 1)
Size
£517.00
- SKU:
- 362516
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ile30-Lys511 from human CECR1 expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- CECR1 encodes a member of a subfamily of the adenosine deaminase protein family. The encoded protein may act as a growth factor and have adenosine deaminase activity. It may be responsible for some of the phenotypic features associated with cat eye syndrome. Two transcript variants encoding distinct isoforms have been identified for this gene. The deduced protein contains 511aa and shows sequence similarity to insect and mollusk growth factors. Highest expression was in adult heart, lung, lymphoblasts, spleen, and placenta, as well as in fetal lung, liver, and kidney. Expression was weaker in adult pancreas, skeletal muscle, and liver, and faint in adult and fetal brain. In situ hybridization of a 35-day human embryo detected CECR1 mRNA in the outflow tract and atrium of the heart, the VII/VIII cranial nerve ganglion, the notochord, and the placenta. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice