362493
CDH5 (Cadherin 5, CD144, 7B4, Cadherin 5 Type 2, VE-Cadherin, Cadherin, Vascular Endothelial)
Size
£505.00
- SKU:
- 362493
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa59-382 of rat CDH5 expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- Cadherin-5, though member of the family of cadherins has been shown to be functionally as well as structurally distinct from classical cadherins (e.g. E-, N-, P-cadherins). Through its function and location cadherin-5 has been named VE-cadherin. VE-cadherin belongs to the adhesion molecules responsible for cellular interactions. The vascular endothelial cadherin (VE-cadherin) gene encodes a Ca2 -dependent cell adhesion molecule required for the organization of interendothelial junctions. This gene is exclusively and constitutively expressed in endothelial cells. The corresponding protein, an endothelial-specific cadherin, is localized at the intercellular junctions. VE-cadherin mediates homophilic, calcium-dependent aggregation and cell-to-cell adhesion. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.3-2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice