362469
CD7 (Cluster Of Differentiation 7, GP40, LEU9, TP41, Tp40, p41 Protein, T-cell Antigen CD7, T-cell Leukemia Antigen, T-cell surface antigen Leu-9)
Size
£524.00
- SKU:
- 362469
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ala26-Glu134 of human CD7, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- CD7 is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. The CD7 antigen is a cell surface glycoprotein found on thymocytes and mature T cells. It is one of the earliest antigens to appear on cells of the T-lymphocyte lineage and the most reliable clinical marker of T-cell acute lymphocytic leukemia. Aruffo and Seed (1987) isolated and sequenced a full-length CD7 cDNA as well as a cDNA for an unusual intron-bearing precursor. They found that COS cells expressing CD7 do not bind IgM. Schanberg et al. (1991) isolated and characterized the human CD7 gene and its 5-prime flanking region; the gene comprises 4 exons that span 3.5 kb. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice