CCL4L1 (Chemokine C-C-Motif Ligand 4 Like Protein 1, LAG1, CCL4L, LAG1, SCYA4L, Monocyte adherence-induced protein 5-alpha, Small-inducible cytokine A4-like, Lymphocyte activation gene 1, Macrophage inflammatory 1-beta)

Size

£626.00

SKU:: 362435
Application:: WB
Purity:: Purified by Protein A and peptide affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Ala24-Asn92 of human CCL4L1 expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:: C-C motif chemokine 4-like is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. This protein is similar to CCL4 which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals; most individuals have 1-5 copies in the diploid genome, although rare individuals do not contain this gene at all. The human genome reference assembly contains two copies of this gene. This record represents the more centromeric gene. Modi et al. (2001) stated that ACT2 is synonymous with CCL4, SCYA4, and MIP1B, while LAG1 is synonymous with CCL4L and SCYA4L. Colobran et al. (2005) showed that both CCL4 and CCL4L generate splice variants lacking exon 2. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-APMGSDP PTACCFSYTA RKLPRNFVVD YYETSSLCSQ PAVVFQTKRG KQVCADPSES WVQEYVYDLE LN Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice