CCL1 (Chemokine C-C-Motif Ligand 1, SCYA1, I-309, TCA3, P500, SISe, Small Inducible Cytokine A1, T Lymphocyte Secreted Protein I-309)

Size

£524.00

SKU:: 362431
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Lys24-Lys96 of human CCL1 expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:: Chemokine (C-C motif) ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines. The inflammatory cytokine I-309 is one of the small inducible chemotactic and inflammatory peptides which have a hydrophobic leader sequence typical of secreted proteins; in many cases the products have indeed been demonstrated to be secreted. Comparison of aa sequences of the gene products show that they share numerous conserved aa’s, most notably 4 cysteine residues that are arranged in a characteristic motif. The superfamily is divided into 2 subfamilies, which are called CC or CXC, depending on whether the protein has 2 adjacent cysteine residues or has a single aa separating the 2 cysteine residues, respectively. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice