362369
CACYBP (SIP, GIG5, PNAS-107, RP1-102G20.6, S100A6BP, S100A6-binding protein, Siah-interacting protein)
Size
£626.00
- SKU:
- 362369
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ala2-Phe228 of human CACYBP expressed in E. coli
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Calcyclin-binding protein is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. The full-length SIP cDNA encodes a predicted 228aa protein. Sequence analysis of the shortest cDNA derived by 2-hybrid screening revealed an 8aa difference in the deduced open reading frame followed by a stop codon, resulting in a predicted 80aa protein, SIP-short (SIPS). SIPS arises by alternative splicing. The full-length human SIP protein shares 93% aa identity with the mouse Sip protein, 40% identity with a counterpart in Drosophila, and 20% identity with the human SGT1 protein. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice