362287
BLNK (B-Cell Linker Protein, BASH, BLNK-s, Ly57, SLP65, B-Cell Adapter Containing A SH2 Domain Protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65kD)
Size
£524.00
- SKU:
- 362287
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ser65-Thr314 of human BLNK, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- Fu et al. (1998) identified a novel BLNK encodes a 456aa polypeptide with basic, acidic, proline-rich, and SH2 domains. An alternatively spliced product called BLNK-S lacks basepairs 760 to 828 within the proline-rich domain. The murine Blnk protein shares 82% identity with human BLNK. There appeared to be no alternatively spliced form of mouse BLNK. BLNK shows greatest homology to the SLP76 (601603) linker protein. BLNK mRNA is predominantly expressed in the spleen, although some level of expression can be seen in liver, kidney, and pancreas. Expression of BLNK proteins was detected only in B-cell lines. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- SDDFDS DYENPDEHSD SEMYVMPAEE NADDSYEPPP VEQETRPVHP ALPFARGEYI DNRSSQRHSP PFSKTLPSKP SWPSEKARLT STLPALTALQ KPQVPPKPKG LLEDEADYVV PVEDNDENYI HPTESSSPPP EKAPMVNRST KPNSSTPASP PGTASGRNSG AWETKSPPPA APSPLPRAGK KPTTPLKTTP VASQQNASSV CEEKPIPAER HRGSSHRQEA VQSPVFPPAQ KQIHQKPIPL PRFT Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice