362160
APOE (AApolipoprotein E, Apo-E, AD2, Apoprotein, Alzheimer Disease 2, E4-Associated,Late Onset)
Size
£495.00
- SKU:
- 362160
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Gln111-Lys314 of mouse APOF, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- Apolipoprotein F is predominantly associated with low density lipoprotein and functions as an inhibitory regulator of cholesteryl ester transfer protein (CETP). Apolipoprotein F, a minor apolipoprotein in human plasma, was isolated and partially characterized by Olofsson et al. (1978). By PCR of a human hepatoma cell line cDNA library using primers based on the N-terminal sequence of purified APOF, Day et al. (1994) cloned full-length APOF. The deduced 308aa proprotein has a 22aa N-terminal signal peptide, and its C-terminal half contains the mature APOF peptide, which is released by proteolytic processing. The mature 162aa hydrophobic APOF peptide has a calculated molecular mass of 17.4kD and contains sites for N- and O-glycosylation. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- QALIHHLQEL QKSGHTDREV SVDALSSALQ LLAWEQPGPK RAKRSISNTD CDNDQEQSVH NVVDLLPAVG TYYNLGTALY YAIKNCSDKA KERGRDGAID LGYDLLMAMV GASGGPAGAV ITAALKPAMK AGVQRLIQYY YDEKEVTTPQ PEVTTHQPET GKDATTDIGV VEEIAMSNFV SEVESTTSNW EWPLLKNYGV LAYK Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice