362127
ANXA11 (Annexin A11, ANX-A11, ANX11, CAP50,56 kDa autoantigen, Calcyclin-associated annexin 50)
Size
£626.00
- SKU:
- 362127
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Met1-Asp505 of human ANXA11, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Annexin A11 is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Exon 1 is untranslated, and intron 1 spans about 20 kb. The human ANXA11 gene has the same general structure as the mouse gene; however, EST database analysis indicated that human ANXA11 transcripts also use variably spliced exons 1b and 1c, which can lengthen the 5-prime UTR. The intronic sequences of the mouse and human ANXA11 genes contain several types of repetitive elements, including retroviral long terminal repeats. The mouse promoter region contains a remnant LINE-1 insertion not found in the human gene. The 5-prime flanking region of the ANXA11 gene contains a CpG island and MYOD, SP1, and glucocorticoid response elements, but no proximal TATA or CAAT boxes. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice