AHNAK (Desmoyokin, AHNAKRS, AHNAK Nucleoprotein, Neuroblast differentiation-associated protein AHNAK)

Size

£626.00

SKU:: 362058
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Met1-Asp300 of human AHNAK, expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:: The first of these genes identified encoded the cell surface protein CD44, an integral membrane glycoprotein that is the principal receptor for hyaluronate on the cell surface. A second gene, originally designated PM227, attracted their attention because its expression appeared to be coordinated with that of CD44. The amino acid sequence of AHNAK suggested secondary structure with a periodicity of 2.33 residues per turn. Individual chains could associate to form a 7- or 8-stranded barrel. The resulting structure would be a polyionic rod with length as great as 1.2 microns. Preliminary evidence indicated that the protein resides predominantly within the nucleus, but no function had been discerned. The highly conserved repeated elements were, for the most part, 128aa long. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice