362003
ADAMTS19 (A Disintegrin And Metalloproteinase With Thrombospondin 19, ADAM Metallopeptidase With Thrombospondin Type 1 Motif 19)
Size
£544.00
- SKU:
- 362003
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Tyr325-Pro686 of human ADAMTS19, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- ADAMTS19 is a member of the large ADAMTS family of zinc-dependent proteases. The deduced protein contains an N-terminal signal peptide, followed by a propeptide; a metalloprotease catalytic domain that includes the Zn-binding motif; a disintegrin-like domain; a central thrombospondin I (THBS1)-like motif; a cysteine-rich domain; a spacer region; 4 C-terminal THBS1 repeats; and a protease-lacunin (PLAC)-like domain. It also has 5 N-glycosylation sites. ADAMTS19 shares 56% sequence identity with ADAMTS17, including 88% identity within the catalytic domains. PCR analysis revealed that ADAMTS19 is expressed in fetal lung, but not in any adult tissues examined. Expression was detected in an osteosarcoma cDNA library. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice