362002
ADAMTS16 (A Disintegrin And Metalloproteinase With Thrombospondin 16, ADAM Metallopeptidase With Thrombospondin Type 1 Motif 16)
Size
£544.00
- SKU:
- 362002
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Leu290-Pro641 of human ADAMTS16, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- ADAMTS16 is a member of the large ADAMTS family of zinc-dependent proteases. The deduced protein contains an N-terminal signal peptide, followed by a propeptide; a metalloprotease catalytic domain that includes the Zn-binding motif; a disintegrin-like domain; a central thrombospondin I (THBS1)-like motif; a cysteine-rich domain; a spacer region; and 3 C-terminal THBS1 repeats. It also has 7 N-glycosylation sites. ADAMTS16 shares 57% sequence identity with ADAMTS18, including 85% identity within the catalytic domains. PCR analysis revealed that ADAMTS16 is expressed in fetal lung and kidney and in adult prostate and ovary.Rat Adamts16, which encodes a 1221aa protein, and they detected prominent expression in rat kidney as well as thymus, lung, heart, liver and spleen. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice