361583
EphA2 Receptor (EphA2, Ephrin Type A Receptor 2) (Chimeric)
Size
£840.00
- SKU:
- 361583
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Soluble human sEphA2, residues 183-510.
- Clone:
- 1C1 (recomb)
- Format:
- Supplied as a liquid in PBS, pH 7.2, 0.02% Proclin-300.
- Extra Details:
- Recombinant monoclonal antibody to EphA2 Receptor with variable regions (i.e. specificity) from the original hybridoma 1C1. This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format. Manufactured using a proprietary recombinant platform technology. Manufactured using a proprietary recombinant platform technology. This antibody binds to human Ephrin type-A receptor 2, a receptor tyrosine kinase that binds to membrane-bound ephrin-A ligands residing on adjacent cells, triggering contact-dependent signaling into neighboring cells. Involved in pattern formation during development, angiogenesis and osteoblastogenesis. Eph2A has also been found to be expressed in a variety of cancers. This antibody acts as an agonist of Eph2A signaling. Applications: Suitable for use in Flow Cytometry, ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice