CD38 (ADP-ribosyl Cyclase 1, Cyclic ADP-ribose Hydrolase, EC 3.2.2.5, Cyclic ADP-ribose Hydrolase 1, cADPr Hydrolase 1, T10, p45, NAD(+) Nucleosidase) (Chimeric)

Size

£840.00

SKU:: 361552
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Viable cells (1x10E7) of the human cell line, BJAB (Human Burkitt lymphoma B cell line), which was were injected intraperitoneally into 8-week-old BALB/c mice.
Clone:: HB7 (recomb)
Format:: Supplied as a liquid in PBS, pH 7.2, 0.02% Proclin-300.
Extra Details:: Recombinant monoclonal antibody to CD38 with variable regions (i.e., specificity) from the hybridoma HB7. This chimeric rabbit antibody was made using the variable domain sequences of the original mouse IgG1 format. Manufactured using a proprietary recombinant platform technology. CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion, signal transduction and calcium signaling. This antibody binds to an epitope between aa273-285 of human CD38, an ~45kD type II transmembrane protein, expressed on essentially all pre-B lymphocytes, plasma cells, and thymocytes. Also present on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. Bimodally expressed during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. Applications: Suitable for use in Flow Cytometry and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice