360180
Eotaxin-2, Recombinant, Human (CCL24)
Size
£381.00
- SKU:
- 360180
- Molecular Weight:
- 8.8
- Purity:
- ≥98% (SDS-PAGE, HPLC). Endotoxin: ≤0.1ng/ug (1EU/mg)
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Supplied as a lyophilized powder in PBS, pH 7.4. Reconstitute with sterile ddH2O, 0.1% BSA to 0.1-1mg/ml.
- Extra Details:
- Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3, including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 amino acid residues for the murine homolog, without C-terminal truncation). Eotaxin-2 contains the four conserved cysteine residues present in CC chemokines. Recombinant human Eotaxin-2 is an 8.8kD protein containing 78 amino acid residues. Recombinant protein corresponding to human Eotaxin-2, expressed in E. coli. Molecular Weight: ~8.8kD (78aa) Biological Activity: Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50-100ng/ml. Amino Acid Sequence: VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O, 0.1% BSA. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice