351843
IP6K3 (Inositol Hexakisphosphate Kinase 3)
Size
£626.00
- SKU:
- 351843
- Purity:
- Purified
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to residues surrounding Ala140 of human IP6K3.
- Clone:
- D9O7J
- Format:
- Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 0.1mg/ml BSA, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Inositol hexakisphosphate kinase 3 (IP6K3) is a member of the inositol hexakisphosphate kinase family (1). These kinases are essential for producing inositol pyrophosphates (1). IP6K3 is highly expressed in the cerebellar Purkinje cells, interacts with adducin and spectrin, and plays an important role in determining the cytoskeletal organization and function of these cells (1). In addition, the expression of IP6K3 increases upon treatment with titanium dioxide nanoparticles suggesting a role for IP6K3 in the genotoxicity caused by these nanoparticles (2). Applications: Suitable for use in Western Blot, Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:1000, incubate membrane with diluted primary antibody in 5% nonfat dry milk, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight. Immunoprecipitation: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice