IBMX (3-Isobutyl-1-methylxanthine)

Size

£326.00

SKU:: 351831
Molecular Weight:: 222.3
Purity:: Highly Purified (~98%)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 28822-58-4
Format:: Supplied as a lyophilized powder. For a 250mM stock, reconstitute the 50mg in 899.7ul DMSO.
Extra Details:: 3-isobutyl-1-methylxanthine (IBMX) is a nonselective inhibitor of cAMP and cGMP phosphodiesterases (PDEs). Research studies show that IBMX inhibits many members of the PDE family, with the exceptions of PDE8A, PDE8B, and PDE9 (1-4). Treatment of cells with IBMX promotes accumulation of cAMP and cGMP, which leads to activation of cyclic- nucleotide- regulated protein kinases (5,6). Additional research indicates that IBMX can promote neuronal progenitor cell maturation in vitro (7). Formula: C10H14N4O2 Solubility: Soluble in DMSO up to ~222mg/ml (1M) with warming. Soluble in DMF or ethanol at 5mg/ml. Molecular Weight: 222.30g/mol Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.