TIPIN, Recombinant, Human, aa1-301, His-Tag (TIMELESS interacting protein)

Size

£512.00

SKU:: 351527
Molecular Weight:: 36.9
Purity:: ~85% (SDS-PAGE)
Storage Conditions:: -20°C/-70°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.15M sodium chloride, 1mM DTT, 10% glycerol.
Extra Details:: TIPIN belongs to the CSM3 family. This protein is required for normal progression of S-phase and important for cell survival after DNA damage or replication stress. TIPIN may be specifically required for the ATR- CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Source: Recombinant protein corresponding to aa1-301 from human TIPIN, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~36.9kD (324aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMLEPQEN GVIDLPDYEH VEDETFPPFP PPASPERQDG EGTEPDEESG NGAPVPVPPK RTVKRNIPKL DAQRLISERG LPALRHVFDK AKFKGKGHEA EDLKMLIRHM EHWAHRLFPK LQFEDFIDRV EYLGSKKEVQ TCLKRIRLDL PILHEDFVSN NDEVAENNEH DVTSTELDPF LTNLSESEMF ASELSRSLTE EQQQRIERNK QLALERRQAK LLSNSQTLGN DMLMNTPRAH TVEEVNTDED QKEESNGLNE DILDNPCNDA IANTLNEEET LLDQSFKNVQ QQLDATSRNI TEAR Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.