NRMT, Recombinant, Human, aa1-223, His-Tag (N-terminal Xaa-Pro-Lys N-methyltransferase1 Isoform a, AD-003, C9orf32, HOMT1A, METTL11A, NTM1A, NTMT1)

Size

£512.00

SKU:: 351400
Molecular Weight:: 28.1
Purity:: ~95% (SDS-PAGE)
Storage Conditions:: -20°C/-70°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.15M sodium chloride, 10% glycerol.
Extra Details:: NTMT1 is also known as N-terminal Xaa-Pro-Lys N-methyltrasferase1 isoform a. NTMT1 is catalyzes the transfer of the methyl group from the S-adenosyl-l-methionine to the protein alpha-amine, resulting in formation of S-adenosyl-l-homocysteine and alpha-N-methylated proteins. NTMT1 is an interesting potential anticancer target because it is overexpressed in gastrointestinal cancers and plays an important role in cell mitosis. Source: Recombinant protein corresponding to aa1-223 from human NTMT1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~28.1kD (248aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSEFMTSEV IEDEKQFYSK AKTYWKQIPP TVDGMLGGYG HISSIDINSS RKFLQRFLRE GPNKTGTSCA LDCGAGIGRI TKRLLLPLFR EVDMVDITED FLVQAKTYLG EEGKRVRNYF CCGLQDFTPE PDSYDVIWIQ WVIGHLTDQH LAEFLRRCKG SLRPNGIIVI KDNMAQEGVI LDDVDSSVCR DLDVVRRIIC SAGLSLLAEE RQENLPDEIY HVYSFALR Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.