Aprataxin, Recombinant, Human, aa1-168, His-Tag (APTX, AXA1)

Size

£512.00

SKU:: 351089
Molecular Weight:: 23.9
Purity:: ≥95% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 100mM sodium chloride, 0.1mM PMSF, 20% glycerol.
Extra Details:: Aprataxin is a member of the histidine triad (HIT) superfamily, some of which have nucleotide- binding and diadenosine polyphosphate hydrolase activities. Aprataxin may play a role in single- stranded DNA repair. Mutations in the gene have been associated with neurological disorder known as ataxia oculomotor apraxia-1. Recombinant protein corresponding to aa1-168 from human Aprataxin, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~23.9kD (205aa) Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMQD PKMQVYKDEQ VVVIKDKYPK ARYHWLVLPW TSISSLKAVA REHLELLKHM HTVGEKVIVD FAGSSKLRFR LGYHAIPSMS HVHLHVISQD FDSPCLKNKK HWNSFNTEYF LESQAVIEMV QEAGRVTVRD GMPELLKLPL RCHECQQLLP SIPQLKEHLR KHWTQ Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.