SUMO2/3 (Small Ubiquitin-related modifier 2, SuMO-2, SuMO-3, Sentrin-2, HSMT3, SMT3B, SMT3H2, Small Ubiquitin-related modifier 2 SMT3 suppressor of mif two 3 homolog 2 (S, cerevisiae), HSMT 3, Sentrin 2, Sentrin2, Small Ubiquitin like modifier 2, Small Ubiquitin related modifier 2, SMT 3B, SMT3 homolog 2, SMT3 suppressor of mif two 3 homolog 2, Sumo2, Sumo3, Ubiquitin like Protein SMT3B.Small Ubiquitin-related modifier 3, SMT3A, SMT3H1, Sumo-3, Sumo3, Sumo 3)

Size

£438.00

SKU:: 350310
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa1-93 from human SUMO2 expressed in E. coli.
Clone:: 16C92
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 10% glycerol.
Extra Details:: SUMO (small ubiquitin-related modifier) is the best-characterized member of a growing family of ubiquitin-related proteins. 8-11kD that covalently modify various intracellular proteins. It resembles ubiquitin in its structure, its ability to be ligated to other proteins. SUMO regulates cellular function of a variety of target proteins. SUMO proteins are expressed as their precursor forms. Cleavage of the residues after the GG region of these precursors by SUMO-specific proteases in maturation is a prerequisite for subsequent sumoylation. Notably, SUMO2 and SUMO3 precursors have 96% sequence identity, and recent studies have shown protein substrates conjugated with SUMO2 or SUMO3 have similar, if not identical, biological consequences. Applications: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunofluorescence: 1:250-500 Western Blot: 1:250-500 Optimal dilutions to be determined by the researcher. Hybridoma: FO myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice