RAB6B, Recombinant, Human, aa1-208, His-Tag (Ras-related protein Rab-6B)

Size

£512.00

SKU:: 350221
Molecular Weight:: 25.6
Purity:: ≥95% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.1M sodium chloride, 1mM DTT, 20% glycerol.
Extra Details:: RAB6B, also known as ras-related protein Rab-6B, belongs to Rab6 family of the small GTPase superfamily. The Rab6 subfamily consists of three different isoforms: Rab6A, Rab6A' and Rab6B. Both Rab6A and Rab6A' are ubiquitously expressed whereas Rab6B is predominantly expressed in brain. Rab6 is a key regulator in the retrograde transfer from endosomes via the Golgi to the ER and may function in retrograde tansport in neuronal cells. Source: Recombinant protein corresponding to aa1-208 of human RAB6B, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~25.6kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSAGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR TVRLQLWDTA GQERFRSLIP SYIRDSTVAV VVYDITNLNS FQQTSKWIDD VRTERGSDVI IMLVGNKTDL ADKRQITIEE GEQRAKELSV MFIETSAKTG YNVKQLFRRV ASALPGMENV QEKSKEGMID IKLDKPQEPP ASEGGCSC Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.