IL-32 (Interleukin 32 Isoform A, IL-32, Natural killer Cells Protein 4(NK4), Tumor Necrosis factor alpha-inducing Factor (TAIF), Interleukin 32, Interleukin 32 Isoform A IL 32alpha, IL 32beta, IL 32delta, IL 32gamma, Interleukin 32, Natural killer Cells Protein 4, NK 4, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd, il32)

Size

£438.00

SKU:: 350001
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa1-131 from human IL32 expressed in E. coli.
Clone:: 16C58
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 10% glycerol.
Extra Details:: The gene encoding IL32 is located on human chromosome 16p13.3 and is organized into eight exons. IL32 is mainly expressed in natural killer cells, T cells, epithelial cells, and blood monocytes. It can induce the proinflammatory cytokines TNFalpha and IL1beta in murine peritoneal macrophages as well as in phorbol ester-differentiated human THP1 cells. In the inflamed lesions of chronic pancreas, the ductal expression of IL32 was markedly increased. Pancreatic duct cells are the local source of IL32, and IL32 may play an important role in inflammatory responses and pancreatic cancer growth. Recently, a synergism between IL32 and other well characterized players in innate immunity has been documented. Applications: Suitable for use in Immunocytochemistry/Immunofluorescence, ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: FO myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice