FkBP4 (FK506 binding Protein 4, FKBP52, FKBP59, HBI, Hsp56, p52, PPIase, FK506 binding Protein 4 52kD FK506 binding Protein, FKBP 4, FKBP 52, FKBP 59, FKBP4, FKBP52 Protein, FKBP59, Hsp 56, HSP binding immunophilin, p59 Protein, PPIase, Rotamase, Peptidyl prolyl cis trans Isomerase, Peptidylprolyl cis trans Isomerase, T Cell FK506 binding Protein 59kD)

Size

£438.00

SKU:: 349918
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa1-459 from human FkBP4 expressed in E. coli.
Clone:: 16C48
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 10% glycerol.
Extra Details:: FkBP4, also known as FkBP52, is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a component of unactivated mammalian steroid receptor complexes and may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000-1:2000 Immunohistochemistry: 1:50-100 Optimal dilutions to be determined by the researcher. Hybridoma: FO myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.