FKBP14 (Peptidyl-prolyl cis-trans Isomerase FKBP14, FKBP22, Peptidyl-prolyl cis-trans Isomerase FKBP14, 22kD FK506 Binding Protein, FK506 Binding Protein 14 (22kD), FK506 Binding Protein 14, FKBP 22, FKBP22, Peptidyl prolyl cis trans Isomerase, PPIase, Rotamase)

Size

£438.00

SKU:: 349916
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa20-211 from human FKBP14 expressed in E. coli.
Clone:: 16C47
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 10% glycerol.
Extra Details:: The FK506-binding proteins (FKBPs) are a unique group of chaperones found in a wide variety of organisms. The gene encoding FKBP14 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Many of these functions are mediated by specific domains that adopt distinct tertiary conformations. In humans, FKBP14 possess variable numbers of FKBP domains and are associated with the endoplasmic reticulum (ER). FK506 Binding Protein 14, 22KD (FKBP14) subcellular located cytoplasm, endoplasmic reticulum lumen. FKBP14 majer molecular functions are calcium ion binding, isomerase activity, peptidyl-prolyl cis-trans isomerase activity. Applications: Suitable for use in ELISA, Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Hybridoma: FO myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice