EGFR (ERBB, ERBB1, Epidermal Growth Factor Receptor, HER1, PIG61, Epidermal Growth Factor Receptor, Urogastrone, Proto-Oncogene c-ErbB-1, Oncogene ERBB, Cell proliferation inducing Protein 61, Cell Growth inhibiting Protein 40, Avian erythroblastic leukemia viral (verbb) Oncogene homolog)

Size

£438.00

SKU:: 349879
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa424-605 from human EGFR expressed in E. coli.
Clone:: 16C40
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 10% glycerol.
Extra Details:: Epidermal growth factor receptor (EGFR) is a 170kD membrane protein first identified as a binding partner of EGF. Also, EGFR phosphorylated itself (autophosphorylation) in response to EGF treatment. The overexpression of EGFR in various epithelial tumors was widely reported and it has been substantiated that deregulation of EGFR itself and its signaling pathways an important role in human cancers. Applications: Suitable for use in Immunofluorescence, ELISA, Western Blot. Other applications not tested. Recommended Dilution: Immunofluorescence: 1:250 Western Blot: 1:250 Optimal dilutions to be determined by the researcher. Hybridoma: FO myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.