CIB1, Recombinant, Human, aa1-191, His-Tag (Calcium and integrin binding 1, CIB, KIP, Kinase interacting protein, SIP2-28, SNK interacting protein2-28, Calmyrin)

Size

£512.00

SKU:: 349788
Molecular Weight:: 23
Purity:: ≥95% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris, pH 8.0, 5mM DTT.
Extra Details:: CIB1 (Calcium and integrin binding 1) is regulatory protein with 50% homology to calmodulin and calcineurin B, that encodes a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. Also CIB1 is widely expressed and binds to a number of effectors, such as integrin alpha IIb, PAK1, and polo-like kinases, in different tissues. Source: Recombinant protein corresponding to aa1-191 of human CIB1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~23kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGGSGSRLSK ELLAEYQDLT FLTKQEILLA HRRFCELLPQ EQRTVESSLR AQVPFEQILS LPELKANPFK ERICRVFSTS PAKDSLSFED FLDLLSVFSD TATPDIKSHY AFRIFDFDDD GTLNREDLSR LVNCLTGEGE DTRLSASEMK QLIDNILEES DIDRDGTINL SEFQHVISRS PDFASSFKIV L Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.