ATOH1, Recombinant, Human, aa158-354 (Protein atonal homolog 1)

Size

£512.00

SKU:: 349704
Molecular Weight:: 21.3
Purity:: ≥85% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.4M urea, 10% glycerol.
Extra Details:: ATOH1, also known as protein atonal homolog 1, activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. This protein may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. Source: Recombinant protein corresponding to aa158-354 of human ATOH1 expressed in E. coli. Molecular Weight: ~21.3kD Amino Acid Sequence: MKQRRLAANA RERRRMHGLN HAFDQLRNVI PSFNNDKKLS KYETLQMAQI YINALSELLQ TPSGGEQPPP PPASCKSDHH HLRTAASYEG GAGNATAAGA QQASGGSQRP TPPGSCRTRF SAPASAGGYS VQLDALHFST FEDSALTAMM AQKNLSPSLP GSILQPVQEE NSKTSPRSHR SDGEFSPHSH YSDSDEAS Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.