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348275

VEGF Coregulated Chemokine 1, active (CXCL17), Recombinant, Human

Size

£411.00

SKU:
348275
Molecular Weight:
11.5
Purity:
≥96% as determined by SDS-PAGE and HPLC.
Storage Conditions:
-20°C
Supplier:
United States Biological
Format:
Lyophilized from 0.2um filtered PBS, pH 7.4
Extra Details:
Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections. {ECO:0000269|PubMed:16455961, ECO:0000269|PubMed:16989774, ECO:0000269|PubMed:17307946}. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0ug/ml, corresponding to a specific activity of > 200 IU/mg. Sequence: SSLNPGVARG HRDRGQASRR WLQEGGQECE CKDWFLRAPR RKFMTVSGLP KKQCPCDHFK GNVKKTRHQR HHRKPNKHSR ACQQFLKQCQ LRSFALPL Molecular Weight: 11.5kD PubMed ID: 16989774; 12975309; 14702039; 15489334; 15340161; 16455961; 17307946 Gene Name: CXCL17,VCC1,UNQ473/PRO842 Swiss Prot: Q6UXB2 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice