Tumor Necrosis Factor Receptor Superfamily Member 17, active (TNFRSF17), Recombinant, Human

Size

£411.00

SKU:: 348260
Molecular Weight:: 5.4
Purity:: ≥98% as determined by SDS-PAGE and HPLC.
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Lyophilized from 0.2 um filtered 30% acetonitrile, 0.1% TFA
Extra Details:: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40ng/ml, corresponding to a specific activity of ＞ 2.5x10e4 IU/mg in the presence of 100ng/ml human APRIL. Sequence: AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA Molecular Weight: 5.4kD PubMed ID: 1396583; 8165126; 11528522; 17825416; 10493829; 15616553; 10903733; 10801128; 10973284; 10908663; 12721620; 15542592 Gene Name: TNFRSF17,BCM,BCMA Swiss Prot: Q02223 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.