348242
Thymic Stromal Lymphopoietin, active (TSLP), Recombinant, Human
Size
£518.00
- SKU:
- 348242
- Molecular Weight:
- 15.1
- Purity:
- ≥98% as determined by SDS-PAGE and HPLC.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Lyophilized from 0.2um filtered 20mM PBS, pH 7.4, 150mM NaCl
- Extra Details:
- Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. {ECO:0000269|PubMed:11418668, ECO:0000269|PubMed:11480573, ECO:0000269|PubMed:17242164}.; Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. {ECO:0000269|PubMed:24850429}. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human IL-7Rα and human TSLP R co-transfected murine BaF3 pro-B cells is less than 0.3ng/ml, corresponding to a specific activity of ＞ 3.3x10e6 IU/mg. Sequence: MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC LEQVSQLQGL WRRFNRPLLK QQ Molecular Weight: 15.1kD PubMed ID: 11418668; 11480573; 15372022; 15489334; 17242164; 24850429 Gene Name: TSLP Swiss Prot: Q969D9 Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice