Probetacellulin, cleaved to Betacellulin, active (BTC), Recombinant, Human

Size

£411.00

SKU:: 348210
Molecular Weight:: 9
Purity:: ≥98% as determined by SDS-PAGE and HPLC.
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Lyophilized from 0.2um filtered PBS, pH 7.4, with 0.02% Tween 20
Extra Details:: Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. {ECO:0000269|PubMed:8570211}. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 0.05ng/ml, corresponding to a specific activity of ＞ 2.0x10e7 IU/mg. Sequence: DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY Molecular Weight: 9.0kD PubMed ID: 8439318; 15489334; 8144591; 8919026; 8570211; 10867024; 12074582 Gene Name: BTC Swiss Prot: P35070 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.