Fibroblast Growth Factor 1, active (FGF1), Recombinant, Human

Size

£411.00

SKU:: 348039
Molecular Weight:: 17.5
Purity:: ≥97% (SDS-PAGE and HPLC.)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Lyophilized from 0.2um filtered PBS, pH 7.4, with 2mM EDTA, 0.5mM DTT, 5% Trehalose
Extra Details:: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. {ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:20145243, ECO:0000269|PubMed:8663044}. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 0.5ng/ml, corresponding to a specific activity of ＞2x10e6IU/mg in the presence of 10ug/ml of heparin. Sequence: MAEGEITTFT ALTEKFNLPP GNYKKPKLLY CSNGGHFLRI LPDGTVDGTR DRSDQHIQLQ LSAESVGEVY IKSTETGQYL AMDTDGLLYG SQTPNEECLF LERLEENHYN TYISKKHAEK NWFVGLKKNG SCKRGPRTHY GQKAILFLPL PVSSD Molecular Weight: 17.5kD PubMed ID: 3523756; 2590193; 2474753; 1693186; 1717925; 1372643; 7504343; 14702039; 15372022; 15489334; 2393407; 2427112; 3527167; 3778488; 3964259; 3732516; 1885605; 8663044; 11432880; 11964394; 16597617; 18400376; 20863990; 15863030; 20094046; 22321063; 1702556; 8652550; 9655399; 10830168; 11069186; 10618369; 11847269; 14732692; 7521397; 8950275; 9719643; 20145243; 20220137 Gene Name: FGF1, FGFA Swiss Prot: P05230 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice