C-X-C motif chemokine 2, active (CXCL2), Recombinant, Human

Size

£518.00

SKU:: 348001
Molecular Weight:: 7.9
Purity:: ≥97% (SDS-PAGE and HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Lyophilized from 0.2um filtered PBS, pH 7.4
Extra Details:: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. {ECO:0000269|PubMed:10725737}. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100ng/ml. Sequence: APLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN Molecular Weight: 7.9kD PubMed ID: 2201751; 2078213; 2217207; 15489334; 2341726; 10725737; 10600366 Gene Name: CXCL2, GRO2, GROB, MIP2A, SCYB2 Swiss Prot: P19875 Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.