C-C motif chemokine 18, active (CCL18), Recombinant, Human

Size

£518.00

SKU:: 347951
Molecular Weight:: 7.9
Purity:: ≥97% (SDS-PAGE, HPLC). Endotoxin: ≤1EU per 1ug (LAL).
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder from PBS, pH 7.4. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.
Extra Details:: Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. Full length recombinant protein corresponding to aa21-89 of human mature CCL18, tag free expressed in E. coli. Swiss/UniProt Accession: P55774. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 1-10ng/ml. Sequence: AQVGTNKELC CLVYTSWQIP QKFIVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA Molecular Weight: 7.9kD PubMed ID: 9233607; 9570561; 9192897; 10049593; 10087196; 19054851; 15489334; 9129202; 11745396; 11978786; 23742785 Gene Name: CCL18, AMAC1, DCCK1, MIP4, PARC, SCYA18 Swiss Prot: P55774 Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice