339672
WDR1 (WD repeat-containing protein 1, Actin-interacting protein 1, AIP1, NORI-1)
Size
£800.00
- SKU:
- 339672
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Human WDR1
- Format:
- Supplied as a liquid in PBS, pH 7.3, 0.09% sodium azide, 50% glycerol.
- Extra Details:
- WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60aa’s, which commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms involving signal transduction, apoptosis, transcriptional regulation, cell cycle control. WD repeats serve as sites for protein-protein interaction and some seem to mediate the assembly of protein complexes. With 11 WD repeats, WDR1 (WD repeat domain 1), also known as AIP1 or NORI-1, is a 606aa protein that localizes to the cytoskeleton and is a member of the WD repeat AIP1 family. Existing as two alternatively spliced isoforms, WDR1 induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice