VEGFR1 (Phospho-Tyr1213)

Size

£518.00

SKU:: 339440
Application:: WB
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Peptide corresponding to the sequence around phosphorylation site of Tyrosine 1213(V-R-Y(p)-V-N) derived from Human VEGFR1.
Format:: Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:: Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.Raghu H, et al. (2012) Mol Oncol 6, 33-47 Ito N, Huang K, Claesson-Welsh L (2001) Cell Signal 13, 849-54 Ito N, Wernstedt C, Engstr m U, Claesson-Welsh L (1998) J Biol Chem 273, 23410-8 Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.