Synuclein-pan

Size

£544.00

SKU:: 336357
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to human synuclein.
Format:: Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:: May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.Eirene Kontopoulos, Hum. Mol. Genet., Oct 2006; 15: 3012 - 3023. Heather Snyder, J. Biol. Chem., Mar 2005; 280: 7562 - 7569. Wanli W. Smith, J. Neurosci., Jun 2005; 25: 5544 - 5552. Yuxin Fan, Hum. Mol. Genet., Oct 2006; 15: 3002 - 3011. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:3000 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.